SELENOM Rabbit Polyclonal Antibody (CAB16660)
- SKU:
- CAB16660
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | SELENOM Rabbit Polyclonal Antibody |
SKU: | CAB16660 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-130 of human SELENOM (NP_536355.1). |
Sequence: | LNRL KEVK AFVT QDIP FYHN LVMK HLPG ADPE LVLL GRRY EELE RIPL SEMT REEI NALV QELG FYRK AAPD AQVP PEYV W |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SELM; SEPM; SELENOM |
Positive Sample: | Raji,A-431,Mouse kidney,Mouse heart,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | endoplasmic reticulum lumen, Golgi apparatus, perinuclear region of cytoplasm |
Calculated MW: | 16kDa |
Observed MW: | 16kDa |
The protein encoded by this gene belongs to the selenoprotein M/SEP15 family. The exact function of this protein is not known. It is localized in the perinuclear region, is highly expressed in the brain, and may be involved in neurodegenerative disorders. Transgenic mice with targeted deletion of this gene exhibit increased weight gain, suggesting a role for this gene in the regulation of body weight and energy metabolism. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal.
Purification Method: | Affinity purification |
Gene ID: | 140606 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |