The SELE Polyclonal Antibody (PAC029816) is a valuable tool for researchers studying SELE, a cell adhesion molecule involved in the recruitment of leukocytes to sites of inflammation. This antibody, raised in rabbits, is highly specific for human SELE and has been validated for use in Western blot applications. By detecting and analyzing the SELE protein, researchers can gain insights into its role in immune response and inflammation.SELE, also known as E-selectin, plays a crucial role in the adhesion of leukocytes to the endothelium, facilitating their migration into tissues during inflammatory processes.
Dysregulation of SELE expression has been implicated in various inflammatory conditions, making it a promising target for research in areas such as immunology and cardiovascular disease. Understanding the function of SELE can provide valuable insights for developing therapies targeting inflammation and immune response modulation.
Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.
Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.
