The Secretogranin-3 Polyclonal Antibody (CAB7799) is a valuable tool for researchers studying Secretogranin-3, a protein involved in regulating secretion and neurotransmitter processing. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in immunohistochemistry and Western blot applications. By binding to the Secretogranin-3 protein, researchers can visualize and analyze its expression in various tissues and cell types, making it ideal for studies in neurobiology and endocrinology.Secretogranin-3 is known to play a role in the regulated secretion of hormones and neuropeptides, making it a key player in processes such as stress response, pain modulation, and metabolism regulation.
Dysregulation of Secretogranin-3 has been implicated in disorders like diabetes, obesity, and neurodegenerative diseases, highlighting its importance in physiological and pathological conditions. Studying the function of Secretogranin-3 with this antibody can provide valuable insights into its role in health and disease, paving the way for potential therapeutic interventions.
Product Name:
SCG3 Rabbit Polyclonal Antibody
SKU:
CAB7799
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 199-468 of human SCG3 (NP_037375.2).
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
29106
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SCG3 antibody (CAB7799) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
