The Secretogranin-2 Polyclonal Antibody (CAB6425) is a valuable tool for researchers studying Secretogranin-2, a protein involved in the regulation of hormone secretion and neurotransmitter storage. This antibody, produced in rabbits, is highly specific for Secretogranin-2 in human samples and has been validated for use in Western blot applications. By binding to the Secretogranin-2 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it ideal for investigations in endocrinology, neurobiology, and cancer research.
Secretogranin-2 is a key player in the exocytosis process, facilitating the release of hormones and neurotransmitters from secretory cells. Its role in vesicle trafficking and secretion makes it a promising target for studies on hormone regulation, synaptic transmission, and neuroendocrine signaling. Researchers exploring the mechanisms underlying hormonal disorders, neurological diseases, and cancer progression can benefit from the unique insights provided by the Secretogranin-2 Polyclonal Antibody.
Product Name:
SCG2 Rabbit Polyclonal Antibody
SKU:
CAB6425
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-320 of human SCG2 (NP_003460.2).
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.
Purification Method:
Affinity purification
Gene ID:
7857
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SCG2 antibody (CAB6425) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
