The Secretin Receptor Polyclonal Antibody (CAB3125) is a vital tool for researchers studying the secretin receptor, a key player in regulating digestive processes and metabolic functions. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By targeting the secretin receptor protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential component for investigations in gastrointestinal physiology and potential therapeutic targets.The secretin receptor is a critical mediator of secretin hormone activity, playing a crucial role in regulating pancreatic function, bile secretion, and gut motility.
Dysregulation of the secretin receptor has been linked to digestive disorders, such as pancreatitis and gallstone formation, underscoring the importance of further research into its function and potential therapeutic interventions. Utilizing the Secretin Receptor Polyclonal Antibody (CAB3125) is a valuable strategy for gaining insights into the intricate mechanisms of digestive health and developing novel strategies for treating related conditions.
Product Name:
SCTR Rabbit Polyclonal Antibody
SKU:
CAB3125
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 151-461 of human SCTR (P47872).
The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism.
Purification Method:
Affinity purification
Gene ID:
6344
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse liver, using SCTR antibody (CAB3125).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
