SEC62 Rabbit Polyclonal Antibody (CAB18589)
- SKU:
- CAB18589
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SEC62 Rabbit Polyclonal Antibody |
SKU: | CAB18589 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 258-399 of human SEC62 (NP_003253.1). |
Sequence: | GRHH FWFL PNLT ADVG FIDS FRPL YTHE YKGP KADL KKDE KSET KKQQ KSDS EEKS DSEK KEDE EGKV GPGN HGTE GSGG ERHS DTDS DRRE DDRS QHSS GNGN DFEM ITKE ELEQ QTDG DCEE DEEE ENDG ETPK SSHE KS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HTP1; TP-1; Dtrp1; TLOC1; SEC62 |
Positive Sample: | Hep G2,NIH/3T3,C6 |
Cellular Localization: | endoplasmic reticulum, rough endoplasmic reticulum |
Calculated MW: | 46kDa |
Observed MW: | 50kDa |
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.
Purification Method: | Affinity purification |
Gene ID: | 7095 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |