The SEC61G Polyclonal Antibody (PAC031604) is a cutting-edge tool for researchers studying SEC61G, a crucial component of the protein translocation channel. This antibody, generated in rabbits, exhibits high specificity and reactivity with human samples, making it an excellent choice for Western blot applications. By targeting the SEC61G protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential tool for investigations in protein translocation and related cellular processes.SEC61G is an essential subunit of the SEC61 complex, which is responsible for the translocation of proteins across the endoplasmic reticulum membrane.
Studies have shown that dysregulation of SEC61G can lead to various diseases, including cancer and neurodegenerative disorders. By investigating the function of SEC61G, researchers can gain valuable insights into protein translocation mechanisms and potentially uncover new therapeutic targets for these diseases. The SEC61G Polyclonal Antibody is a valuable asset for any research project aiming to unravel the complexities of protein translocation and its implications for human health.
Antibody Name:
SEC61G Antibody (PACO31604)
Antibody SKU:
PACO31604
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Protein transport protein Sec61 subunit γ protein (1-32AA)
Immunohistochemistry of paraffin-embedded human colon cancer using PACO31604 at dilution of 1:100.
Background:
Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across endoplasmic reticulum (ER).
Synonyms:
Protein transport protein Sec61 subunit gamma, SEC61G
UniProt Protein Function:
Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across endoplasmic reticulum (ER).
UniProt Protein Details:
NCBI Summary:
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the gamma-subunit protein. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
