[KO Validated] SEC61B Rabbit Polyclonal Antibody (CAB15788)
- SKU:
- CAB15788
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] SEC61B Rabbit Polyclonal Antibody |
SKU: | CAB15788 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-96 of human SEC61B (NP_006799.1). |
Sequence: | MPGP TPSG TNVG SSGR SPSK AVAA RAAG STVR QRKN ASCG TRSA GRTT SAGT GGMW RFYT EDSP GLKV GPVP VLVM SLLF IASV FMLH IWGK YTRS |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | SEC61B; 1B |
Positive Sample: | HeLa,HepG2,SH-SY5Y,Mouse stomach,Rat liver,Rat stomach |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Single-pass membrane protein. |
Calculated MW: | 10kDa |
Observed MW: | 12kDa |
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.
Purification Method: | Affinity purification |
Gene ID: | 10952 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |