The SEC61A1 Polyclonal Antibody (CAB11658) is a valuable tool for researchers studying SEC61A1, a key protein involved in protein translocation across the endoplasmic reticulum membrane. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting SEC61A1 in human samples, making it reliable for use in Western blotting and other immunoassays.SEC61A1 is essential for the proper functioning of the protein translocation machinery, playing a crucial role in protein synthesis, folding, and trafficking within cells. Dysregulation of SEC61A1 has been implicated in various diseases, including cancer and genetic disorders.
By targeting SEC61A1 with this polyclonal antibody, researchers can investigate its role in cellular processes and disease pathology, providing insights that may lead to the development of novel therapeutic strategies.Overall, the SEC61A1 Polyclonal Antibody (CAB11658) is a valuable reagent for investigating the function and regulation of SEC61A1 in biological systems, offering a comprehensive tool for advancing research in cell biology, molecular biology, and biomedical sciences.
Product Name:
SEC61A1 Rabbit Polyclonal Antibody
SKU:
CAB11658
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 310-420 of human SEC61A1 (NP_037468.1).
The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits.
Purification Method:
Affinity purification
Gene ID:
29927
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SEC61A1 Rabbit pAb (CAB11658) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
