SEC24D Rabbit Polyclonal Antibody (CAB16091)
- SKU:
- CAB16091
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SEC24D Rabbit Polyclonal Antibody |
SKU: | CAB16091 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 830-1000 of human SEC24D (NP_001304995.1). |
Sequence: | AASQ LILP DSMK VLPV YMNC LLKN CVLL SRPE ISTD ERAY QRQL VMTM GVAD SQLF FYPQ LLPI HTLD VKST MLPA AVRC SESR LSEE GIFL LANG LHMF LWLG VSSP PELI QGIF NVPS FAHI NTDM TLLP EVGN PYSQ QLRM IMGI IQQK RPYS MKLT IVKQ REQP EMV |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | CLCRP2; SEC24D |
Positive Sample: | LO2,BxPC-3,A-375,DU145,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endoplasmic reticulum membrane, Golgi apparatus membrane, perinuclear region |
Calculated MW: | 113kDa |
Observed MW: | 113kDa |
The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration. Mutations in this gene have been associated with Cole-Carpenter syndrome, a disorder affecting bone formation, resulting in craniofacial malformations and bones that break easily. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 9871 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |