The SEC23IP Polyclonal Antibody (CAB15398) is a valuable tool for researchers studying SEC23IP, a protein involved in intracellular transport and vesicle trafficking. This antibody, produced in rabbits, demonstrates high specificity and sensitivity for detecting SEC23IP in human samples, making it ideal for use in Western blot applications. By binding to the SEC23IP protein, this antibody enables the precise detection and analysis of SEC23IP in various cell types, supporting investigations in cell biology and molecular biology.SEC23IP is a key component of the COPII vesicle coat complex, which is responsible for transporting proteins from the endoplasmic reticulum to the Golgi apparatus. Dysfunction of SEC23IP can lead to disruptions in intracellular transport processes, impacting cell function and potentially contributing to disease development.
Research on SEC23IP is essential for understanding these cellular mechanisms and their implications for conditions such as neurodegenerative disorders and metabolic diseases.By utilizing the SEC23IP Polyclonal Antibody (CAB15398), researchers can further explore the role of SEC23IP in intracellular transport pathways and its potential involvement in various physiological and pathological processes. This antibody offers precise and reliable detection of SEC23IP, facilitating insightful investigations into cell biology and disease mechanisms.
Product Name:
SEC23IP Rabbit Polyclonal Antibody
SKU:
CAB15398
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 600-940 of human SEC23IP (NP_009121.1).
This gene encodes a member of the phosphatidic acid preferring-phospholipase A1 family. The encoded protein is localized to endoplasmic reticulum exit sites and plays a critical role in ER-Golgi transport as part of the multimeric coat protein II complex. An orthologous gene in frogs is required for normal neural crest cell development, suggesting that this gene may play a role in Waardenburg syndrome neural crest defects. Alternatively spliced transcript variants have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
11196
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SEC23IP Rabbit pAb (CAB15398) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
