The SEC23B Polyclonal Antibody (CAB15131) is a valuable tool for researchers studying SEC23B, a key component of the COPII coat involved in protein transport from the endoplasmic reticulum to the Golgi apparatus. This antibody, raised in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to SEC23B protein, this antibody enables precise detection and analysis in a variety of cell types, making it well-suited for investigations in cell biology and protein trafficking.SEC23B is essential for the proper functioning of the secretory pathway, playing a critical role in maintaining cellular homeostasis and ensuring the correct transport of proteins within cells.
Disruptions in SEC23B function have been associated with various diseases, including genetic disorders and cancer, making it a significant target for research aimed at understanding disease mechanisms and developing targeted therapies.By providing a reliable tool for studying SEC23B, the SEC23B Polyclonal Antibody offers researchers the opportunity to deepen their understanding of protein trafficking processes and uncover new insights into the role of SEC23B in health and disease. This antibody holds promise for advancing knowledge in cell biology and potentially contributing to the development of innovative therapeutic strategies in the future.
Product Name:
Sec23B Rabbit Polyclonal Antibody
SKU:
CAB15131
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human Sec23B (NP_006354.2).
The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants have been identified in this gene.
Purification Method:
Affinity purification
Gene ID:
10483
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Sec23B Rabbit pAb (CAB15131) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
