The SEC23A Polyclonal Antibody (CAB12101) is a valuable tool for researchers studying SEC23A, a key protein involved in the transport of vesicles from the endoplasmic reticulum to the Golgi apparatus. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to SEC23A, researchers can accurately detect and analyze the protein in various cell types, making it an essential component for studies in cell biology and protein trafficking.SEC23A plays a critical role in maintaining cellular function by ensuring the proper sorting and delivery of cargo proteins to their designated locations within the cell.
Dysregulation of SEC23A function has been linked to various diseases, including neurological disorders and certain types of cancer. Understanding the mechanisms by which SEC23A operates is essential for developing targeted therapies to address these conditions and improve overall health outcomes. By utilizing the SEC23A Polyclonal Antibody, researchers can further explore the intricate details of protein transport and trafficking pathways, ultimately advancing our knowledge of cellular biology and disease mechanisms.
Product Name:
Sec23A Rabbit Polyclonal Antibody
SKU:
CAB12101
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human Sec23A (NP_006355.2).
The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It is part of a protein complex and found in the ribosome-free transitional face of the endoplasmic reticulum (ER) and associated vesicles. This protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The encoded protein is suggested to play a role in the ER-Golgi protein trafficking.
Purification Method:
Affinity purification
Gene ID:
10484
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Sec23A Rabbit pAb (CAB12101) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
