The SEC22A Polyclonal Antibody (PAC040142) is a valuable tool for researchers studying SEC22A, a protein involved in membrane trafficking and protein transport within cells. This antibody, generated in rabbits, displays high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to SEC22A, the antibody enables precise detection and analysis of this important protein in various cell types, making it an ideal choice for studies in cell biology and molecular biology.SEC22A is a key player in intracellular membrane fusion events, facilitating the transport of cargo vesicles to their target membranes.
Its role in these essential cellular processes makes it a target of interest for researchers studying mechanisms of cell communication, organelle biogenesis, and protein secretion. By understanding the function and regulation of SEC22A, researchers can gain insights into fundamental cellular processes and potentially uncover new therapeutic targets for various diseases related to intracellular trafficking dysfunction.
Immunofluorescent analysis of MCF-7 cells using PACO40142 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO40142 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human liver tissue using PACO40142 at dilution of 1:100.
Background:
May be involved in vesicle transport between the ER and the Golgi complex.
Synonyms:
Vesicle-trafficking protein SEC22a (SEC22 vesicle-trafficking protein homolog A) (SEC22 vesicle-trafficking protein-like 2), SEC22A, SEC22L2
UniProt Protein Function:
SEC22A: May be involved in vesicle transport between the ER and the Golgi complex. Belongs to the synaptobrevin family.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 3q21.1Cellular Component: SNARE complexMolecular Function: protein binding; SNAP receptor activity; SNARE binding; transporter activityBiological Process: exocytosis; vesicle fusion with Golgi apparatus
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene belongs to the member of the SEC22 family of vesicle trafficking proteins. This protein has similarity to rat SEC22 and may act in the early stages of the secretory pathway. [provided by RefSeq, Nov 2008]
