The SEC14L4 Polyclonal Antibody (PAC041774) is a valuable tool for researchers studying SEC14L4, a protein involved in lipid metabolism and intracellular lipid transport. This antibody, developed and tested in rabbits, has high reactivity with human samples and is optimized for use in Western blot applications.SEC14L4 is a crucial player in lipid homeostasis, maintaining the balance of lipids within cells and helping to regulate lipid-related processes such as membrane trafficking and signaling. Dysregulation of SEC14L4 has been linked to conditions such as metabolic disorders, neurodegenerative diseases, and cancer, making it an important target for further investigation.
By specifically binding to SEC14L4, this antibody allows for precise detection and analysis of the protein in various cell types, aiding researchers in understanding its role in cellular function and disease pathways. Its versatility and reliability make it an essential tool for studies in lipid biology, metabolism, and related fields.
Antibody Name:
SEC14L4 Antibody (PACO41774)
Antibody SKU:
PACO41774
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human SEC14-like protein 4 protein (201-360AA)
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO41774 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human liver tissue using PACO41774 at dilution of 1:100.
Background:
Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids.
Synonyms:
SEC14-like protein 4 (Tocopherol-associated protein 3), SEC14L4, TAP3
UniProt Protein Function:
SEC14L4: Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids.Protein type: Unknown functionChromosomal Location of Human Ortholog: 22q12.2Molecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is highly similar to the protein encoded by the Saccharomyces cerevisiae SEC14 gene. The SEC14 protein is a phophatidylinositol transfer protein that is essential for biogenesis of Golgi-derived transport vesicles, and thus is required for the export of yeast secretory proteins from the Golgi complex. The specific function of this protein has not yet been determined. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2009]
