The SEC14L2 Polyclonal Antibody (CAB10586) is a valuable tool for researchers studying SEC14L2, a cytosolic protein involved in lipid metabolism and intracellular protein trafficking. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By binding to the SEC14L2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for investigations in the fields of lipid biology and cell biology.SEC14L2 is known to play a crucial role in the maintenance of lipid homeostasis and the regulation of intracellular membrane trafficking processes.
Its involvement in cellular functions such as lipid transfer and vesicle trafficking makes it a potential target for research on lipid-related disorders and cellular transport mechanisms. Understanding the function of SEC14L2 is essential for uncovering the mechanisms underlying lipid metabolism and intracellular trafficking, which could have implications for the development of treatments for conditions related to these processes.
Product Name:
SEC14L2 Rabbit Polyclonal Antibody
SKU:
CAB10586
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-270 of human SEC14L2 (NP_001191133.1).
This gene encodes a cytosolic protein which belongs to a family of lipid-binding proteins including Sec14p, alpha-tocopherol transfer protein, and cellular retinol-binding protein. The encoded protein stimulates squalene monooxygenase which is a downstream enzyme in the cholesterol biosynthetic pathway. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
23541
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SEC14L2 Rabbit pAb (CAB10586) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
