The SEC11C Polyclonal Antibody (PAC041010) is a valuable tool for researchers studying SEC11C, a protein involved in protein trafficking and processing within the cell. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting applications. By targeting the SEC11C protein, this antibody allows for the detection and analysis of SEC11C in a variety of cell types, making it ideal for research in cell biology and protein processing.
SEC11C plays a crucial role in the secretion and maturation of proteins within the endoplasmic reticulum and Golgi apparatus. Its involvement in protein trafficking pathways makes it an important target for studying cellular processes related to protein synthesis and secretion. Researchers interested in understanding the mechanisms of protein trafficking and processing can utilize this antibody to investigate the function of SEC11C in various cellular contexts.
Antibody Name:
SEC11C Antibody (PACO41010)
Antibody SKU:
PACO41010
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Signal peptidase complex catalytic subunit SEC11C protein (49-192AA)
Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO41010 at dilution of 1:100.
Background:
Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.
Synonyms:
Signal peptidase complex catalytic subunit SEC11C (EC 3.4.21.89) (Microsomal signal peptidase 21 kDa subunit) (SPase 21 kDa subunit) (SEC11 homolog C) (SEC11-like protein 3) (SPC21), SEC11C, SEC11L3 SPC21 SPCS4C
UniProt Protein Function:
SEC11L3: Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Belongs to the peptidase S26B family.Protein type: Membrane protein, integral; EC 3.4.21.89; ProteaseChromosomal Location of Human Ortholog: 18q21.32Cellular Component: endoplasmic reticulum membrane