The SEC11A Polyclonal Antibody (CAB10552) is a cutting-edge tool for researchers studying SEC11A, a protein involved in intracellular protein trafficking. This antibody, produced using rabbit immunization, exhibits strong reactivity with human samples and has been validated for Western blotting techniques. By specifically binding to SEC11A, this antibody allows for precise detection and analysis of the protein in various cell types, making it an essential reagent for investigations in cell biology and molecular biology.SEC11A is a key player in the regulation of protein transport within the cell, making it a vital target for research into mechanisms of intracellular communication and signaling.
Its function in protein processing and trafficking suggests potential implications in various cellular processes, such as protein folding and maturation. By delving into the role of SEC11A, researchers may uncover new insights into fundamental biological processes, paving the way for innovative therapeutic approaches targeting protein trafficking disorders and related conditions.
Product Name:
SEC11A Rabbit Polyclonal Antibody
SKU:
CAB10552
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 37-145 of human SEC11A (NP_055115.1).
Endoplasmic reticulum membrane, Microsome membrane, Single-pass type II membrane protein.
Calculated MW:
21kDa
Observed MW:
21kDa
This gene encodes a member of the peptidase S26B family. The encoded protein is an 18kDa subunit of the signal peptidase complex and has been linked to cell migration and invasion, gastric cancer and lymph node metastasis. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.
Purification Method:
Affinity purification
Gene ID:
23478
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SEC11A Rabbit pAb (CAB10552) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.