SDHD Rabbit Polyclonal Antibody (CAB16240)
- SKU:
- CAB16240
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SDHD Rabbit Polyclonal Antibody |
SKU: | CAB16240 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human SDHD (NP_002993.1). |
Sequence: | HLSP SHHS GSKA ASLH WTSE RVVS VLLL GLLP AAYL NPCS AMDY SLAA ALTL HGHW GLGQ VVTD YVHG DALQ KAAK AGLL ALSA LTFA GLCY FNYH DVGI C |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PGL; CBT1; CWS3; PGL1; QPs3; SDH4; cybS; CII-4; MC2DN3; SDHD |
Positive Sample: | mouse brain,mouse heart,mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion inner membrane, Multi-pass membrane protein. |
Calculated MW: | 17kDa |
Observed MW: | 17kDa |
This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 6392 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |