The SDHAF2 Polyclonal Antibody (CAB16204) is a valuable tool for researchers studying the role of SDHAF2, a protein involved in mitochondrial complex II assembly and function. This polyclonal antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.SDHAF2, also known as succinate dehydrogenase complex assembly factor 2, is essential for the proper assembly and activity of mitochondrial complex II, which plays a crucial role in cellular energy production and metabolism.
Dysregulation of SDHAF2 has been linked to various metabolic disorders and cancers, making it a promising target for therapeutic interventions.By binding specifically to SDHAF2 protein, this antibody enables precise detection and analysis of SDHAF2 in different cell types, facilitating research in mitochondrial biology, metabolic diseases, and cancer. Understanding the function and regulation of SDHAF2 can provide valuable insights into the mechanisms underlying these diseases and guide the development of novel treatment strategies.
Product Name:
SDHAF2 Rabbit Polyclonal Antibody
SKU:
CAB16204
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human SDHAF2 (NP_060311.1).
This gene encodes a mitochondrial assembly factor needed for the flavination of a succinate dehydrogenase complex subunit (SDHA), which is required for activity of the succinate dehydrogenase complex. Mutations in this gene are associated with paraganglioma.
Purification Method:
Affinity purification
Gene ID:
54949
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SDHAF2 Rabbit pAb (CAB16204) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
