The SDHA Rabbit Monoclonal Antibody offered by Assay Genie is a high-quality antibody designed for research involving SDHA, a subunit of succinate dehydrogenase complex, an enzyme involved in the citric acid cycle and electron transport chain. This antibody is raised in rabbits and is highly reactive with human samples, making it a valuable tool for studying mitochondrial function and metabolism.Validated for use in Western blot applications, this antibody specifically binds to the SDHA protein, allowing for easy detection and analysis in various cell types. Its reliability and specificity make it ideal for research in biochemistry, cell biology, and metabolism.
SDHA is essential for cellular energy production and has been implicated in various diseases, including cancer and neurodegenerative disorders. By studying the function of SDHA using this antibody, researchers can gain valuable insights into the role of mitochondrial dysfunction in disease development and progression.Overall, the SDHA Rabbit Monoclonal Antibody from Assay Genie is a valuable tool for researchers studying mitochondrial function, metabolism, and related diseases.
Product Name:
SDHA Rabbit Monoclonal Antibody
SKU:
CAB13852
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 550-650 of human SDHA (P31040).
This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6389
Clone Number:
ARC0726
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using SDHA Rabbit mAb (CAB13852) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
