The SDCBP2 Polyclonal Antibody (PAC012067) is a valuable tool for researchers studying SDCBP2, a protein involved in numerous cellular processes including cell signaling, gene expression, and cell proliferation. This antibody is raised in rabbits and has been validated for use in various applications, including Western blotting, immunofluorescence, and immunohistochemistry.SDCBP2, also known as Syntenin-2, is a multi-functional protein that interacts with a variety of binding partners to regulate various cellular functions. Its role in cell signaling pathways and protein-protein interactions makes it a key player in processes such as cell migration, adhesion, and invasion.
Research into SDCBP2's functions can provide insights into cancer progression, metastasis, and potential therapeutic targets.By utilizing the SDCBP2 Polyclonal Antibody, researchers can confidently detect and analyze SDCBP2 protein levels in different cell types and experimental conditions, contributing to a better understanding of its biological significance. This antibody is an essential tool for studies investigating SDCBP2's role in cancer biology, cell signaling, and potential therapeutic applications.
syndecan binding protein (syntenin) 2;SDCBP2;FLJ12256;SITAC18;ST-2 ;
UniProt Protein Function:
Binds phosphatidylinositol 4,5-bisphosphate (PIP2). May play a role in the organization of nuclear PIP2, cell division and cell survival (PubMed:15961997).
NCBI Summary:
The protein encoded by this gene contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins, and PDZ-containing proteins mediate cell signaling and the organization of protein complexes. The encoded protein binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Read-through transcription also exists between this gene and the upstream FKBP1A (FK506 binding protein 1A, 12kDa) gene, as represented in GeneID:100528031. [provided by RefSeq, Sep 2011]
