The Scytovirin Antibody (PACO34058) is a polyclonal antibody designed for research involving Scytovirin, a protein with potent antiviral properties. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various immunological applications, including Western blotting and immunohistochemistry.Scytovirin, derived from a cyanobacterium, has shown promising antiviral activity against a variety of viruses, making it an attractive target for research into antiviral therapies. By binding to the Scytovirin protein, this antibody enables detection and analysis in different cell types, allowing for a better understanding of its function in viral inhibition.
The unique properties of Scytovirin make it a valuable tool for studying viral infections and developing novel antiviral strategies. Researchers in virology, immunology, and antiviral drug development can benefit from utilizing this antibody in their studies to explore the potential of Scytovirin as a therapeutic agent against viral pathogens.
Antibody Name:
Scytovirin Antibody (PACO34058)
Antibody SKU:
PACO34058
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Scytonema varium
Immunogen:
Recombinant Scytonema varium Scytovirin protein (1-95AA)
Has strong anti-HIV activity against T-tropic strains of HIV-1 and weaker activity against M-tropic strains of HIV-1. Inhibits HIV-1 fusion and infection of CD4 LTR beta-gal cells in vitro. Inhibits fusion of HIV infected CEM-SS cells with uninfected CEM-SS cells, and fusion of HIV-1 Env expressing HL2/3 cells with CD4 LTR beta-gal cells. Binds to HIV gp120, HIV gp160 and to a lesser extent HIV gp41. Binding to HIV gp120 is glycosylation dependent. Binds with high specificity to the tetrasaccharide Man-alpha-1,2-Man-alpha-1,6-Man-alpha-1,6-Man and also binds the higher-order oligosaccharides oligomannose 8 and oligomannose 9. Does not bind to monosaccharides, complex or hybrid N-linked oligosaccharides or chitin.
Synonyms:
Scytovirin (SVN)
UniProt Protein Function:
Has strong anti-HIV activity against T-tropic strains of HIV-1 and weaker activity against M-tropic strains of HIV-1. Inhibits HIV-1 fusion and infection of CD4 LTR beta-gal cells in vitro. Inhibits fusion of HIV infected CEM-SS cells with uninfected CEM-SS cells, and fusion of HIV-1 Env expressing HL2/3 cells with CD4 LTR beta-gal cells. Binds to HIV gp120, HIV gp160 and to a lesser extent HIV gp41. Binding to HIV gp120 is glycosylation dependent. Binds with high specificity to the tetrasaccharide Man-alpha-1,2-Man-alpha-1,6-Man-alpha-1,6-Man and also binds the higher-order oligosaccharides oligomannose 8 and oligomannose 9. Does not bind to monosaccharides, complex or hybrid N-linked oligosaccharides or chitin.