The SCYL3 Polyclonal Antibody (PAC037638) is a valuable tool for researchers studying the SCYL3 protein, a key player in cellular signaling pathways. This antibody, generated in rabbits, exhibits high specificity for human samples and is validated for use in Western blotting applications. By targeting the SCYL3 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential tool for investigations in cell biology and cancer research.
SCYL3 is known for its role in intracellular transport and protein trafficking, playing a crucial part in maintaining cellular homeostasis. Its involvement in cell signaling pathways makes it an attractive target for studying various diseases, including cancer and neurodegenerative disorders. By understanding the function of SCYL3, researchers can uncover new insights into disease mechanisms and potentially identify novel therapeutic targets for intervention.
Antibody Name:
SCYL3 Antibody (PACO37638)
Antibody SKU:
PACO37638
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Protein-associating with the carboxyl-terminal domain of ezrin protein (1-688AA)
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO37638 at dilution of 1:100.
Background:
May play a role in regulating cell adhesion/migration complexes in migrating cells.
Synonyms:
Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3), SCYL3, PACE1
UniProt Protein Function:
SCYL3: May play a role in regulating cell adhesion/migration complexes in migrating cells. Belongs to the protein kinase superfamily. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Kinase, protein; Other group; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor); SCY1 familyChromosomal Location of Human Ortholog: 1q24.2Cellular Component: cytoplasm; Golgi apparatus; lamellipodiumMolecular Function: ATP binding; kinase activity; protein bindingBiological Process: cell migration; protein amino acid phosphorylation
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein with a kinase domain and four HEAT repeats. The encoded protein interacts with the C-terminal domain of ezrin, an ERM protein, and may play a role in cell adhesion and migration. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Jun 2012]
