The SCYL2 Polyclonal Antibody (CAB13179) is a crucial tool for researchers studying SCYL2, a protein involved in numerous cellular processes. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to the SCYL2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it essential for immunology and cancer research studies.
SCYL2, also known as a regulator of Golgi morphology, plays a vital role in cell growth, proliferation, and intracellular trafficking. Its involvement in these processes makes it a key target for research in various diseases and disorders. By understanding the function of SCYL2, researchers can gain insights into conditions such as cancer, neurological disorders, and metabolic diseases, leading to the development of potential therapeutic interventions.
Product Name:
SCYL2 Rabbit Polyclonal Antibody
SKU:
CAB13179
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SCYL2 (NP_060458.3).
The protein encoded by this gene associates with clathrin-coated complexes at the plasma membrane and with endocytic coated vesicles. The encoded protein phosphorylates the beta2 subunit of the plasma membrane adapter complex AP2 and interacts with clathrin, showing involvement in clathrin-dependent pathways between the trans-Golgi network and the endosomal system. In addition, this protein has a role in the Wnt signaling pathway by targeting frizzled 5 (Fzd5) for lysosomal degradation. Two transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
55681
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SCYL2 Rabbit pAb (CAB13179) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
