The SCYL1 Polyclonal Antibody (CAB6735) is a specialized tool for researchers studying the SCYL1 protein, which plays a key role in cellular processes such as protein trafficking and cell signaling. Raised in rabbits, this antibody offers high reactivity specifically with human samples and is validated for use in Western blot applications. By binding to the SCYL1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential tool for studies in cell biology and molecular biology.
SCYL1, also known as SCY1-like 1 protein, is involved in regulating intracellular transport and activating signaling pathways crucial for cell function and survival. Its importance in these processes highlights its potential as a target for research into various diseases, including cancer and neurological disorders. By understanding the functions of SCYL1, researchers can uncover new insights into disease mechanisms and potential therapeutic strategies targeting this protein.
Product Name:
SCYL1 Rabbit Polyclonal Antibody
SKU:
CAB6735
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 460-740 of human SCYL1 (NP_065731.3).
This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
57410
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts from wild type(WT) and SCYL1 knockout (KO) 293T(KO) cells, using SCYL1 antibody (CAB6735) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
