The SCO1 Polyclonal Antibody (CAB6734) is a valuable tool for researchers studying SCO1, a protein involved in mitochondrial biogenesis and copper metabolism. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the SCO1 protein, this antibody allows for the detection and analysis of SCO1 levels in various cell types, making it ideal for investigations in the fields of biochemistry and cell biology.SCO1 is a critical component of the mitochondrial respiratory chain, playing a key role in cellular energy production. Dysregulation of SCO1 has been linked to various diseases, including mitochondrial disorders and neurodegenerative conditions.
By studying the function and expression of SCO1, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for treatment.Overall, the SCO1 Polyclonal Antibody is a valuable tool for researchers seeking to better understand the role of SCO1 in mitochondrial function and disease pathology. Its high specificity and reliability make it a valuable asset for studies in biochemistry, molecular biology, and mitochondrial research.
Product Name:
SCO1 Rabbit Polyclonal Antibody
SKU:
CAB6734
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human SCO1 (NP_004580.1).
Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. In yeast, 2 related COX assembly genes, SCO1 and SCO2 (synthesis of cytochrome c oxidase), enable subunits 1 and 2 to be incorporated into the holoprotein. This gene is the human homolog to the yeast SCO1 gene.
Purification Method:
Affinity purification
Gene ID:
6341
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using SCO1 Rabbit pAb (CAB6734) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
