The SCNN1G Polyclonal Antibody (CAB15097) is a valuable tool for research involving the SCNN1G protein, a subunit of the epithelial sodium channel. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to SCNN1G, researchers can effectively detect and analyze this protein in a variety of cell types.SCNN1G is a key player in the regulation of sodium ion transport across epithelial cell membranes, making it essential for maintaining proper fluid balance in the body. Dysregulation of SCNN1G activity has been linked to various health conditions, including hypertension and cystic fibrosis.
Investigating the function of SCNN1G using this antibody can provide valuable insights into the mechanisms underlying these diseases and inform potential therapeutic strategies.Furthermore, the SCNN1G Polyclonal Antibody is an essential tool for researchers studying ion channel function, epithelial transport, and kidney physiology. Its versatility and specificity make it an ideal choice for investigations in areas such as nephrology, pharmacology, and molecular biology. By utilizing this antibody, scientists can advance our understanding of SCNN1G and its role in human health and disease.
Product Name:
SCNN1G Rabbit Polyclonal Antibody
SKU:
CAB15097
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-289 of human SCNN1G (NP_001030.2).
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the gamma subunit, and mutations in this gene have been associated with Liddle syndrome.
Purification Method:
Affinity purification
Gene ID:
6340
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SCNN1G Rabbit pAb (CAB15097) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
