SCNN1A Rabbit Polyclonal Antibody (CAB5538)
- SKU:
- CAB5538
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | SCNN1A Rabbit Polyclonal Antibody |
SKU: | CAB5538 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 105-225 of human SCNN1A (NP_001029.1). |
Sequence: | LFGE YFSY PVSL NINL NSDK LVFP AVTI CTLN PYRY PEIK EELE ELDR ITEQ TLFD LYKY SSFT TLVA GSRS RRDL RGTL PHPL QRLR VPPP PHGA RRAR SVAS SLRD NNPQ VDWK DWKI G |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | BESC2; ENaCa; SCNEA; SCNN1; LIDLS3; PHA1B1; ENaCalpha; SCNN1A |
Positive Sample: | 293T,A-549 |
Conjugate: | Unconjugated |
Cellular Localization: | Apical cell membrane, Cell projection, Multi-pass membrane protein, cilium. |
Calculated MW: | 76kDa |
Observed MW: | 75kDa |
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6337 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |