SCN5A Rabbit Polyclonal Antibody (CAB16665)
- SKU:
- CAB16665
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | SCN5A Rabbit Polyclonal Antibody |
SKU: | CAB16665 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1950-2016 of human SCN5A (NP_932173.1). |
Sequence: | YVMS ENFS RPLG PPSS SSIS STSF PPSY DSVT RATS DNLQ VRGS DYSH SEDL ADFP PSPD RDRE SIV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | HB1; HB2; HH1; IVF; VF1; HBBD; ICCD; LQT3; SSS1; CDCD2; CMD1E; CMPD2; PFHB1; Nav1.5; SCN5A |
Positive Sample: | Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | endoplasmic reticulum, lateral plasma membrane, nucleolus, nucleoplasm, perinuclear region of cytoplasm, plasma membrane, sarcolemma, T-tubule, Z disc |
Calculated MW: | 227kDa |
Observed MW: | 230-280kDa |
The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene have been associated with long QT syndrome type 3 (LQT3), atrial fibrillation, cardiomyopathy, and Brugada syndrome 1, all autosomal dominant cardiac diseases. Alternative splicing results in several transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 6331 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |