SCN1B Rabbit Polyclonal Antibody (CAB10071)
- SKU:
- CAB10071
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SCN1B Rabbit Polyclonal Antibody |
SKU: | CAB10071 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-160 of human SCN1B (NP_950238.1). |
Sequence: | GGCV EVDS ETEA VYGM TFKI LCIS CKRR SETN AETF TEWT FRQK GTEE FVKI LRYE NEVL QLEE DERF EGRV VWNG SRGT KDLQ DLSI FITN VTYN HSGD YECH VYRL LFFE NYEH NTSV VKKI HIEV VDKG ESGA ACPF TV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DEE52; ATFB13; BRGDA5; EIEE52; GEFSP1; SCN1B |
Positive Sample: | SH-SY5Y,A-549,HeLa,MCF7,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 25kDa |
Observed MW: | 30kDa |
Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6324 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |