The SCML2 Polyclonal Antibody (PACO1819) is a valuable tool for researchers studying SCML2, a protein involved in epigenetic regulation and gene expression control. This antibody, generated in rabbits, exhibits high reactivity towards human samples and is validated for use in Western blot applications. By specifically binding to SCML2, the antibody allows for accurate detection and analysis of the protein in various cell types, making it an ideal choice for studies in epigenetics and gene regulation research.
SCML2 is a key player in maintaining chromatin structure and gene silencing, making it essential for the proper functioning of cells. Its involvement in epigenetic processes and gene expression make it a promising target for investigations into developmental disorders, cancer, and other diseases related to abnormalities in gene regulation. Understanding the role of SCML2 is crucial for gaining insights into the mechanisms underlying these conditions and developing potential therapeutic strategies.
Antibody Name:
SCML2 Antibody
Antibody SKU:
PACO01819
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human SCML2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
SCML2; Sex comb on midleg-like protein 2
UniProt Protein Function:
SCML2: a protein of unknown function. Contains a SAM (sterile alpha motif) and two MBT domains.Protein type: Transcription factorChromosomal Location of Human Ortholog: Xp22Cellular Component: nucleus; PcG protein complexMolecular Function: DNA binding; transcription factor activityBiological Process: anatomical structure morphogenesis
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the Polycomb group proteins. These proteins form the Polycomb repressive complexes which are involved in transcriptional repression. The encoded protein binds histone peptides that are monomethylated at lysine residues and may be involved in regulating homeotic gene expression during development. [provided by RefSeq, Jun 2010]
