The SCLT1 Polyclonal Antibody (PAC029760) is a valuable tool for researchers studying SCLT1, a protein involved in cell adhesion and signaling pathways. This antibody is produced in rabbits and has been validated for use in Western blot applications, providing reliable detection and analysis of SCLT1 in human samples. SCLT1, also known as SCARS2, is known to play a role in interaction with other proteins involved in cell adhesion and migration, making it a key player in cellular processes such as wound healing and tissue regeneration.
Research on SCLT1 is important for understanding its functions in normal physiological processes as well as its potential implications in diseases like cancer and developmental disorders.By using the SCLT1 Polyclonal Antibody, researchers can further explore the roles and mechanisms of action of SCLT1 in various cellular contexts, ultimately leading to a better understanding of its potential therapeutic applications in the future.
Antibody Name:
SCLT1 Antibody (PACO29760)
Antibody SKU:
PACO29760
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Sodium channel and clathrin linker 1 protein (1-79AA)
Immunohistochemistry of paraffin-embedded human liver tissue using PACO29760 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human duodenum tissue using PACO29760 at dilution of 1:100.
Background:
Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization.
Synonyms:
Sodium channel and clathrin linker 1 (Sodium channel-associated protein 1), SCLT1, SAP1
UniProt Protein Function:
SCLT1: Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 4q28.2Cellular Component: centriole; centrosome; cytosolBiological Process: cilium biogenesis
UniProt Protein Details:
NCBI Summary:
This gene encodes an adaptor protein. Studies of a related gene in rat suggest that the encoded protein functions to link clathrin to the sodium channel protein type 10 subunit alpha protein. The encoded protein has also been identified as a component of distal appendages of centrioles that is necessary for ciliogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
