The SCLT1 Polyclonal Antibody (PACO12050) is a valuable tool for researchers studying the SCLT1 protein, which is involved in various cellular processes such as cell adhesion and signaling. This antibody, produced in rabbits, exhibits high reactivity towards human samples and has been validated for use in Western blot applications. By specifically targeting the SCLT1 protein, this antibody enables accurate detection and analysis in different cell types, making it suitable for investigations in areas such as cell biology and cancer research.
SCLT1, also known as synaptic cleft leucine-rich repeat transmembrane protein 1, plays a crucial role in cell adhesion processes and is implicated in various physiological functions. Its involvement in cell signaling pathways and cellular interactions makes it a promising target for research on diseases like cancer and neurological disorders. By gaining insights into the function of SCLT1, researchers can potentially develop novel therapeutic strategies targeting this protein for the treatment of related conditions.
sodium channel and clathrin linker 1;SCLT1;CAP1A;FLJ30655;FLJ36042;MGC70542;hCAP-1A ;
UniProt Protein Function:
SCLT1: Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 4q28.2Cellular Component: centriole; centrosome; cytosolBiological Process: cilium biogenesis
UniProt Protein Details:
NCBI Summary:
This gene encodes an adaptor protein. Studies of a related gene in rat suggest that the encoded protein functions to link clathrin to the sodium channel protein type 10 subunit alpha protein. The encoded protein has also been identified as a component of distal appendages of centrioles that is necessary for ciliogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
