Anti-SCGB1A1 Antibody (CAB16998)
- SKU:
- CAB16998
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Anti-SCGB1A1 Antibody (CAB16998)
The SCGB1A1 Polyclonal Antibody (CAB16998) is a valuable tool for researchers studying SCGB1A1, a protein associated with lung development and respiratory diseases. This rabbit-derived antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to SCGB1A1, this antibody allows for the detection and analysis of this protein in various cell types, making it ideal for studies in respiratory biology and pulmonary disease research.SCGB1A1, also known as secretoglobin family 1A member 1, is involved in regulating lung function and protecting the respiratory tract from damage.
Its role in lung development and disease pathogenesis makes it a promising target for investigating conditions such as asthma, chronic obstructive pulmonary disease (COPD), and lung cancer. Understanding the function of SCGB1A1 can provide insights into the mechanisms underlying these respiratory disorders and potentially lead to the development of novel therapeutic strategies.
| Antibody Name: | Anti-SCGB1A1 Antibody |
| Antibody SKU: | CAB16998 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IHC IF |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-91 of human SCGB1A1 (NP_003348.1). |
| Application: | IHC IF |
| Recommended Dilution: | IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-91 of human SCGB1A1 (NP_003348.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | EICP SFQR VIET LLMD TPSS YEAA MELF SPDQ DMRE AGAQ LKKL VDTL PQKP RESI IKLM EKIA QSSL CN |
| Gene ID: | 7356 |
| Uniprot: | P11684 |
| Cellular Location: | |
| Calculated MW: | 9kDa |
| Observed MW: | Refer to figures |
 | Immunohistochemistry - SCGB1A1 Polyclonal Antibody (CAB16998) |
| Synonyms: | SCGB1A1, CC10, CC16, CCPBP, CCSP, UGB, UP-1, UP1 |
| Background: | This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma. |
| UniProt Protein Function: | SCGB1A1: Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2. Belongs to the secretoglobin family. |
| UniProt Protein Details: | Protein type:Secreted; Cell cycle regulation; Secreted, signal peptide; Inhibitor Chromosomal Location of Human Ortholog: 11q12.3 Cellular Component: extracellular space; rough endoplasmic reticulum; nuclear envelope; secretory granule Molecular Function:protein binding; phospholipase A2 inhibitor activity Biological Process: response to drug; negative regulation of interleukin-4 production; response to glucocorticoid stimulus; response to lipopolysaccharide; female pregnancy; negative regulation of transcription from RNA polymerase II promoter; signal transduction; regulation of mRNA stability; response to xenobiotic stimulus; response to silicon dioxide; negative regulation of interleukin-13 production; negative regulation of T cell proliferation; response to ozone; negative regulation of interferon-gamma production; response to cytokine stimulus; negative regulation of catalytic activity; regulation of inflammatory response; negative regulation of interleukin-5 production; embryo implantation Disease: Asthma, Susceptibility To |
| NCBI Summary: | This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma. [provided by RefSeq, May 2010] |
| UniProt Code: | P11684 |
| NCBI GenInfo Identifier: | 112672 |
| NCBI Gene ID: | 7356 |
| NCBI Accession: | P11684.1 |
| UniProt Related Accession: | P11684 |
| Molecular Weight: | 16kDa |
| NCBI Full Name: | Uteroglobin |
| NCBI Synonym Full Names: | secretoglobin family 1A member 1 |
| NCBI Official Symbol: | SCGB1A1Â Â |
| NCBI Official Synonym Symbols: | UGB; UP1; CC10; CC16; CCSP; UP-1; CCPBPÂ Â |
| NCBI Protein Information: | uteroglobin |
| UniProt Protein Name: | Uteroglobin |
| UniProt Synonym Protein Names: | Clara cell phospholipid-binding protein; CCPBP; Clara cells 10 kDa secretory protein; CC10; Secretoglobin family 1A member 1; Urinary protein 1; UP-1; UP1; Urine protein 1 |
| Protein Family: | Uteroglobin |
| UniProt Gene Name: | SCGB1A1Â Â |
| UniProt Entry Name: | UTER_HUMAN |
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SCGB1A1 Rabbit Polyclonal Antibody (CAB16997)
Mouse Uteroglobin (Scgb1a1) ELISA Kit (MOEB0638)
