UniProt Protein Function: | Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth (). |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells. It regulates the uptake of chemically modified low density lipoproteins, including acetylated low density lipoprotein (Ac-LDL), and it may be involved in atherogenesis. This gene is regulated by the transcription factors ZNF444/EZF-2 and SP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013] |
UniProt Code: | Q14162 |
NCBI GenInfo Identifier: | 33598929 |
NCBI Gene ID: | 8578 |
NCBI Accession: | NP_003684.2 |
UniProt Secondary Accession: | Q14162,O43701, Q8NHD2, Q8NHD3, Q8NHD4, Q8NHD5, A8MQ05 |
UniProt Related Accession: | Q14162 |
Molecular Weight: | 91 |
NCBI Full Name: | scavenger receptor class F member 1 isoform 1 |
NCBI Synonym Full Names: | scavenger receptor class F member 1 |
NCBI Official Symbol: | SCARF1Â Â |
NCBI Official Synonym Symbols: | SREC; SREC1; SREC-IÂ Â |
NCBI Protein Information: | scavenger receptor class F member 1 |
UniProt Protein Name: | Scavenger receptor class F member 1 |
UniProt Synonym Protein Names: | Acetyl LDL receptor; Scavenger receptor expressed by endothelial cells 1; SREC-I |
Protein Family: | |
UniProt Gene Name: | SCARF1Â Â |
UniProt Entry Name: | |