The SCARB1 Rabbit Monoclonal Antibody is a specialized tool for researchers studying SCARB1, a cell surface receptor involved in cholesterol metabolism and lipid transport. This monoclonal antibody, generated from rabbit cells, exhibits high specificity and sensitivity for detecting SCARB1 in human samples, making it a valuable asset for research in cardiovascular disease, lipid disorders, and metabolic syndrome.SCARB1, also known as scavenger receptor class B member 1, plays a key role in mediating the uptake of cholesterol from HDL particles, thus influencing cholesterol levels and atherosclerosis development. Research on SCARB1 is essential for understanding the mechanisms underlying lipid metabolism and cardiovascular health, offering insights into potential therapeutic targets for managing dyslipidemia and cardiovascular risk.
The SCARB1 Rabbit Monoclonal Antibody is recommended for Western blot analysis and immunohistochemistry applications, providing reliable results in the investigation of SCARB1 expression and function in various cell and tissue types. With its versatility and precision, this antibody is a valuable resource for advancing research in lipid biology, cardiovascular physiology, and metabolic disorders.
Product Name:
SR-BI Rabbit Monoclonal Antibody
SKU:
CAB0827
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SR-BI (Q8WTV0).
The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2 and facilitates cell entry by the virus, SARS-CoV2.
Purification Method:
Affinity purification
Gene ID:
949
Clone Number:
ARC0334
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using SR-BI Rabbit mAb (CAB0827) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
