The SCARB1 Polyclonal Antibody (CAB1584) is a valuable tool for researchers studying the SCARB1 protein, also known as scavenger receptor class B member 1. SCARB1 plays a crucial role in cholesterol metabolism and transport, specifically in high-density lipoprotein (HDL) cholesterol uptake and reverse cholesterol transport.This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to the SCARB1 protein, this antibody enables accurate detection and analysis in a variety of cell types.
Its reliability and specificity make it a key tool for studies in lipid metabolism, cardiovascular diseases, and atherosclerosis research.The SCARB1 Polyclonal Antibody is essential for investigating the function and regulation of SCARB1 in various physiological and pathological conditions. Understanding the role of SCARB1 in cholesterol homeostasis and its implications in cardiovascular health is vital for developing targeted therapies and interventions for cardiovascular diseases and dyslipidemias.
Product Name:
SR-BI Rabbit Polyclonal Antibody
SKU:
CAB1584
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SR-BI (NP_005496.4).
The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2 and facilitates cell entry by the virus, SARS-CoV2.
Purification Method:
Affinity purification
Gene ID:
949
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SR-BI antibody (CAB1584) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
