The SCARA3 Polyclonal Antibody (PAC036438) is a valuable tool for researchers studying SCARA3, a receptor involved in cellular processes like phagocytosis and immune response regulation. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting SCARA3 in human samples, making it suitable for use in Western blot experiments. By targeting the SCARA3 protein, this antibody enables researchers to investigate its expression and function in various cell types, offering insights into its role in immunology and cancer biology.
SCARA3, also known as scavenger receptor class A member 3, is known to play a role in maintaining cellular homeostasis and immune system function by recognizing and clearing cellular debris and pathogens. Its involvement in immune regulation suggests potential implications in diseases such as cancer and inflammation-related disorders. Through studying SCARA3 with this antibody, researchers can further elucidate its mechanisms and potential therapeutic applications in various disease contexts.
Western blot. All lanes: SCARA3 antibody at 0.8µg/ml. Lane 1: Mouse liver tissue. Lane 2: Mouse kidney tissue. Lane 3: A549 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 66, 53 kDa. Observed band size: 66 kDa.
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO36438 at dilution of 1:100.
Background:
Seems to protect cells by scavenging oxidative molecules or harmful products of oxidation.
Synonyms:
Scavenger receptor class A member 3 (Cellular stress response gene protein), SCARA3, CSR
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a macrophage scavenger receptor-like protein. This protein has been shown to deplete reactive oxygen species, and thus play an important role in protecting cells from oxidative stress. The expression of this gene is induced by oxidative stress. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
