SBDS Rabbit Polyclonal Antibody (CAB5876)
- SKU:
- CAB5876
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SBDS Rabbit Polyclonal Antibody |
SKU: | CAB5876 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human SBDS (NP_057122.2). |
Sequence: | MSIF TPTN QIRL TNVA VVRM KRAG KRFE IACY KNKV VGWR SGVE KDLD EVLQ THSV FVNV SKGQ VAKK EDLI SAFG TDDQ TEIC KQIL TKGE VQVS DKER HTQL EQMF RDIA TIVA DKCV NPET KRPY TVIL IERA MKDI HYSV KTNK STKQ QALE VIKQ LKEK MKIE RAHM RLRF ILPV NEGK KLKE KLKP LIKV IESE DYGQ QLEI VCLI DPGC FREI DELI KKET KGKG SLEV LNLK DVEE GDEK FE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SDS; SDO1; SWDS; CGI-97; SBDS |
Positive Sample: | U-87MG,SKOV3,HepG2,HL-60,Mouse brain,Mouse lung,Rat lung,Rat ovary |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, cytoskeleton, nucleolus, nucleoplasm, spindle. |
Calculated MW: | 29kDa |
Observed MW: | 34kDa |
This gene encodes a highly conserved protein that plays an essential role in ribosome biogenesis. The encoded protein interacts with elongation factor-like GTPase 1 to disassociate eukaryotic initiation factor 6 from the late cytoplasmic pre-60S ribosomal subunit allowing assembly of the 80S subunit. Mutations within this gene are associated with the autosomal recessive disorder Shwachman-Bodian-Diamond syndrome. This gene has a closely linked pseudogene that is distally located.
Purification Method: | Affinity purification |
Gene ID: | 51119 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |