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SBDS Monoclonal Antibody [PAT1E8AT] (CPAB0459)

SKU:
CPAB0459
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT1E8AT
€149
Frequently bought together:

Description

system_update_alt Datasheet

SBDS Monoclonal Antibody [PAT1E8AT] (CPAB0459)

The SBDS Polyclonal Antibody (CPAB0459) is a valuable tool for researchers studying the SBDS protein, which is essential for the Shwachman-Diamond syndrome, a rare genetic disorder characterized by bone marrow failure and an increased risk of leukemia. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications.The SBDS protein is involved in ribosome biogenesis and RNA processing, making it a key player in cellular growth and division. Dysregulation of SBDS has been linked to the development of leukemia and other hematological disorders.

By targeting the SBDS protein, researchers can explore its role in disease pathology and potentially identify novel therapeutic targets for treating Shwachman-Diamond syndrome and related conditions.In summary, the SBDS Polyclonal Antibody is a valuable tool for investigating the SBDS protein's function in cellular processes and disease development. Its high reactivity and specificity make it suitable for a wide range of research applications in molecular biology, genetics, and hematology.

Product Name:SBDS Antibody
Product Sku:CPAB0459
Size:5μg
Host Species:Mouse
Immunogen:Anti-human SBDS mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human SBDS amino acids 1-25 purified from Ecoli.
Clone:PAT1E8AT.
Reactivity:Other bodies
Applications:
Purification Method:SBDS antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:SBDS is part of an extremely preserved protein family which exists from archaea to vertebrates and plants. SBDS protein functions in RNA metabolism and has a role in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Shwachman-Diamond syndrome is a rare autosomal recessive disorder produced by mutations in the SBDS gene.
Synonyms:SDS, SWDS, Shwachman-Bodian-Diamond syndrome, Ribosome Maturation protein SBDS.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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