The SATB2 Polyclonal Antibody (CAB16721) is a valuable tool for researchers studying SATB2, a protein critical for gene regulation and cell differentiation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting applications. By specifically binding to the SATB2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in developmental biology, cancer research, and neurobiology.
SATB2 is a transcription factor that plays a key role in controlling gene expression patterns during development, particularly in the formation of the skull, teeth, and brain. Mutations in the SATB2 gene have been associated with disorders affecting these structures, highlighting the importance of understanding its function. By investigating the role of SATB2 in normal and diseased states, researchers can gain insights into developmental processes and potentially identify new therapeutic targets for a range of conditions.
Product Name:
SATB2 Rabbit Polyclonal Antibody
SKU:
CAB16721
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 634-733 of human SATB2 (NP_001165980.1).
This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling. Defects in this gene are associated with isolated cleft palate and cognitive disability. Alternate splicing results in multiple transcript variants that encode the same protein.
Purification Method:
Affinity purification
Gene ID:
23314
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from LO2 cells, using SATB2 Rabbit pAb (CAB16721) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
