The SATB1 Polyclonal Antibody (CAB5800) is a powerful tool for researchers studying the SATB1 protein, a key regulator of gene expression and chromatin organization. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blotting and immunohistochemistry applications.SATB1, or Special AT-rich Sequence-Binding Protein 1, plays a vital role in the organization of chromatin structure and the regulation of gene expression. Its involvement in various cellular processes, including cell differentiation, proliferation, and immune response, makes it a valuable target for research in immunology, cancer, and developmental biology.
By targeting the SATB1 protein, researchers can gain insight into its function and mechanism of action, paving the way for the development of targeted therapies for diseases where SATB1 dysregulation plays a role. The SATB1 Polyclonal Antibody is a versatile tool for investigating the role of SATB1 in health and disease, offering reliable and sensitive detection in a variety of experimental settings.
Product Name:
SATB1 Rabbit Polyclonal Antibody
SKU:
CAB5800
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 572-763 of human SATB1 (NP_002962.1).
WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
DEFDA; KTZSL; SATB1
Positive Sample:
Jurkat
Conjugate:
Unconjugated
Cellular Localization:
Nucleus, Nucleus matrix, PML body.
Calculated MW:
86kDa
Observed MW:
100kDa
This gene encodes a matrix protein which binds nuclear matrix and scaffold-associating DNAs through a unique nuclear architecture. The protein recruits chromatin-remodeling factors in order to regulate chromatin structure and gene expression.
Purification Method:
Affinity purification
Gene ID:
6304
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Jurkat cells, using SATB1 Rabbit pAb (CAB5800) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
