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SASH1 Rabbit Polyclonal Antibody (CAB15248)

SKU:
CAB15248
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:SASH1 Rabbit Polyclonal Antibody
SKU:CAB15248
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SASH1 (NP_056093.3).
Sequence:MEDA GAAG PGPE PEPE PEPE PEPA PEPE PEPK PGAG TSEA FSRL WTDV MGIL DGSL GNID DLAQ QYAD YYNT CFSD VCER MEEL RKRR VSQD LEVE KPDA SPTS LQLR SQIE ESLG FCSA VSTP EVER KNPL HKSN SEDS SVGK GDWK KKNK YFWQ NFRK NQKG IMRQ TSKG EDVG YVAS EITM SDEE RIQL MMMV KEKM ITIE EALA RLKE YEAQ HRQS AALD PADW PDGS YPTF DGSS NCNS REQS DDET EESV KFKR LHKL VNST RRVR KKLI RVEE MKKP STEG GEEH VFEN SPVL
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:DUH; DUH1; CAPOK; SH3D6A; dJ323M4.1; SASH1
Positive Sample:U-87MG,Mouse lung
Conjugate:Unconjugated
Cellular Localization:cytoplasm
Calculated MW:137kDa
Observed MW:170kDa

This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients.

Purification Method:Affinity purification
Gene ID:23328
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using SASH1 Rabbit pAb (CAB15248) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.

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