The SART3 Polyclonal Antibody (CAB12124) is a valuable tool for researchers studying SART3, a nuclear protein involved in RNA splicing and mRNA export. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications.SART3 plays a crucial role in the regulation of gene expression and is known to be dysregulated in various cancers, making it a potential therapeutic target. By targeting SART3 with this antibody, researchers can study its function in different cellular processes, providing insights into its role in RNA metabolism and its potential implications in disease progression.
With its high reactivity and specificity, the SART3 Polyclonal Antibody is a reliable tool for researchers exploring the complex mechanisms of gene expression and RNA processing. Its use in Western blot applications enables the detection and analysis of SART3 protein levels in various cell types, offering valuable information for studies in molecular biology, cancer research, and beyond.
Product Name:
SART3 Rabbit Polyclonal Antibody
SKU:
CAB12124
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 664-963 of human SART3 (NP_055521.1).
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.
Purification Method:
Affinity purification
Gene ID:
9733
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SART3 Rabbit pAb (CAB12124) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
