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SARS Nucleocapsid Monoclonal (CPAB0417)

SKU:
CPAB0417
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Virus
Applications:
WB
IF
ELISA
€413
Frequently bought together:

Description

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SARS Nucleocapsid Monoclonal (CPAB0417)

The SARS-Nucleocapsid Monoclonal Antibody (CPAB0417) is a vital tool for research in understanding the SARS-CoV-2 virus. This antibody, produced in mice, specifically targets the nucleocapsid protein of the SARS-CoV-2 virus, enabling precise detection and analysis in various samples. Validated for use in applications such as ELISA and immunofluorescence, this antibody is essential for investigating the structure and function of the virus, aiding in the development of diagnostic tests and potential therapeutic interventions.The nucleocapsid protein of SARS-CoV-2 plays a crucial role in viral replication and packaging, making it a key target for research in understanding the mechanisms underlying viral infectivity and host immune responses.

By targeting this specific protein, researchers can gain valuable insights into the virus's pathogenesis and potential vulnerabilities that could be targeted for treatment strategies. The SARS-Nucleocapsid Monoclonal Antibody is a valuable resource for advancing our knowledge of SARS-CoV-2 and developing effective countermeasures against this global health threat.

Product Name:SARS Nucleocapsid Monoclonal
Product Sku:CPAB0417
Size:5μg
Host Species:
Immunogen:SARS Antibody was developed by immunizing mice with a protein fragment amino acids 1-49 from the human SARS Nucleocapsid coronavirus (Genbank accession noNP_828858). SARS-Nucleocapsid, Monoclonal Antibody is protein-G purified.
Clone:
Reactivity:Viral
Applications:Western Blot, Immunofluorescence, ELISA
Purification Method:
Isotype:
Background:SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies.It has recently been shown that SARS is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics.
Synonyms:
Storage Buffer:

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