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SARS Nucleocapsid Biotin Monoclonal Antibody [PT3851] (CPAB0422)

SKU:
CPAB0422
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Virus
Clone:
PT3851
Applications:
ELISA
€2,079
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Description

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SARS Nucleocapsid Biotin Monoclonal Antibody [PT3851] (CPAB0422)

The SARS-Nucleocapsid Biotin Antibody (CPAB0422) is a powerful tool for researchers studying the SARS-CoV-2 virus, specifically targeting the nucleocapsid protein. This polyclonal antibody, raised in rabbits, is highly reactive with samples from SARS-CoV-2 infected cells and is validated for use in various applications such as immunohistochemistry and ELISA.The nucleocapsid protein is essential for viral replication and plays a key role in the pathogenesis of SARS-CoV-2. By detecting and analyzing this protein in infected cells, researchers can gain valuable insights into the virus's life cycle and potential therapeutic targets.

This antibody is ideal for studies in virology, immunology, and vaccine development related to COVID-19.With the ongoing global pandemic, understanding the mechanisms of SARS-CoV-2 infection is crucial for developing effective treatments and vaccines. The SARS-Nucleocapsid Biotin Antibody provides a valuable tool for researchers to further investigate the biology of the virus and aid in the development of strategies to combat COVID-19.

Product Name:SARS Nucleocapsid Biotin Antibody
Product Sku:CPAB0422
Size:100μg
Host Species:
Immunogen:Recombinant protein fragment 1-49 a.aof the SARS nucleoprotein.
Clone:PT3851
Reactivity:Viral
Applications:ELISA
Purification Method:Protein A affinity purified.
Isotype:
Background:SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies.It has recently been shown that SARS is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics.
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Storage Buffer:

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