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SARS-CoV-2 Spike RBD (N501Y) Monoclonal Antibody (CAB21254)

SKU:
CAB21254
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
SARS-CoV-2
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
$167 - $635
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:SARS-CoV-2 Spike RBD (N501Y) Monoclonal Antibody
SKU:CAB21254
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:SARS-CoV-2
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 450-550 of coronavirus SARS-CoV-2 Spike RBD (N501Y) (YP_009724390.1).
Sequence:NYLY RLFR KSNL KPFE RDIS TEIY QAGS TPCN GVEG FNCY FPLQ SYGF QPTY GVGY QPYR VVVL SFEL LHAP ATVC GPKK STNL VKNK CVNF NFNG LTGT G
Tested Applications:WB ELISA
Recommended Dilution:WB,1:1000 - 1:5000
Synonyms:spike glycoprotein; SARS-CoV-2 Spike RBD (N501Y)
Positive Sample:Recombinant SARS-CoV-2 Spike RBD (N501Y) protein
Conjugate:Unmodified
Cellular Localization:nuclear capsid
Calculated MW:141KD
Observed MW:36kDa

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ The structural proteins of SARS-CoV-2 include the envelope protein (E), spike or surface glycoprotein (S), membrane protein (M) and the nucleocapsid protein (N). The spike glycoprotein is found on the outside of the virus particle and gives coronavirus viruses their crown-like appearance. This glycoprotein mediates attachment of the virus particle and entry into the host cell. S protein is an important target for vaccine development, antibody therapies and diagnostic antigen-based tests.

Purification Method:Affinity purification
Gene ID:43740568
Clone Number:ARC52673
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates, using SARS-CoV-2 Spike RBD (N501Y) antibody (CAB21254) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.

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