SARS-CoV-2 Nucleocapsid Recombinant Protein (Active) (RPES7039)
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- SKU:
- RPES7039
- Product Type:
- Recombinant Protein
- Species:
- Virus
Description
| Product Name: | SARS-CoV-2 Nucleocapsid Recombinant Protein (Active) |
| Product Code: | RPES7039 |
| Size: | 50µg |
| Species: | SARS-CoV-2 |
| Expression Host: | HEK293 Cells |
| Synonyms: | SARS-CoV-2 coronavirus NP Protein, SARS-CoV-2 np Protein, SARS-CoV-2 novel coronavirus Nucleoprotein Protein |
| Mol Mass: | 46.4kDa |
| AP Mol Mass: | 50 kDa |
| Tag: | C-His |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | Please contact us for more information. |
| Bio Activity: | Immobilized 2019-nCoV NP Antibody(6G9)-Fc at 5μg/ml(100 μl/well) can bind Recombinant 2019-nCoV Nucleocapsid Protein (Mammalian)-His. The ED50 of 2019-nCoV Nucleocapsid Protein-His is 0.172 ug/ml. |
| Sequence: | Met1-Ala419 |
| Accession: | QHD43423.2 |
| Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation: | Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 150mM NaCl, 50mM Arginine, pH7.5 Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in t |
| Reconstitution: | Not Applicable |
| Background: | Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. |
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