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SARS-CoV-2 (2019-nCoV) S Recombinant Protein RBD (C-mFc-6His tag) (Active)

SKU:
RPES7024
Product Type:
Recombinant Protein
Species:
Virus
€849
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Description

Product Name:SARS-CoV-2 (2019-nCoV) S Recombinant Protein RBD (C-mFc-6His tag) (Active)
Product Code:RPES7024
Size:50µg
Species:SARS-CoV-2
Expression Host:HEK293 Cells
Synonyms:S protein RBD, Spike glycoprotein Receptor-binding domain, S glycoprotein RBD, Spike protein RBD, COVID-19
Mol Mass:52.2kDa
Tag:C-mFc-His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:Please contact us for more information.
Bio Activity:1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human S-RBD, mFc-His tagged protein can bind Anti-SARS-CoV-2 Neutralizing antibody in a linear range of 0.24-15.62 ng/ml. 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) S-RBD, mFc-His tagged protein can bind Human ACE2, hFc Tagged protein in a linear range of 0.488-49.83 ng/ml.
Sequence:Arg319-Phe541
Accession:QHD43416.1
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as Covid19 (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. The spike protein is a type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which accounts for recognizing the cell surface receptor, ACE2. S2 contains basic elements needed for the membrane fusion. Recent publications indicate that S1-RBD domain can induce virus neutralizing-antibody and T cell response.

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